Cancer Diagnostics



  1. Alo, P.L., Visca, P., Botti, C., Galati, G.M., Sebastiani, V., Andreano, T., DiTondo, U., Pizer, E.S. Immunohistochemical expression of human erythrocyte glucose transporter fatty acid synthase in infiltrating breast carcinomas and adjacent typical/atypical hyperplastic or normal breast tissue. Am J Clin Pathol. 116(1):129-134, 2001.

  2. Wang, Y., Kuhajda, F.P. Li, J.N., Pizer, E.S. Han, W.F., Sokoll, L.J., Chan, D.W. Fatty acid synthase (FAS) expression in human breast cancer cell culture supernatants and in breast cancer patients. Cancer Lett. 167(1):99-104, 2001.

  3. Wang, Y., Kuhajda, F. P., and Chan, D. W. Two-site ELISA for the quantitative determination of fatty acid synthase, Clinical Chemistry Acta. 304(1-2):107-15, 2001.

  4. Alo, P. L., Visca, P., Mazzaferro, S., Serpieri, D. E., Mangoni, A., Botti, C., Monaco, S., Carboni, M., Zaraca, F., Trombetta, G., and Di Tondo, U. Immunohistochemical study of fatty acid synthase, Ki67, proliferating cell nuclear antigen, and p53 expression in hyperplastic parathyroids, Annals Diagnostic Pathology. 3: 287-293, 1999.

  5. Pizer ES, Chrest FJ, and Han WF. Growth arrest an pan-cell cycle apoptosis induced by pharmacological inhibition of mammalian fatty acid synthase activity: Sensitization by loss of p53 function, Proceeding of the American Association for Cancer Research. 40: 94, 1999.

  6. Visca, P., Alo, P. L., Del Nonno, F., Botti, C., Trombetta, G., Marandino, F., Filippi, S., Di Tondo, U., and Donnoros, R. P. Immunohistochemical expression of fatty acid synthase, apoptotic-regulating genes, proliferating factors, and ras protein product in colorectal adenomas, carcinomas, and adjacent nonneoplastic mucosa, Clinical Cancer Research. 5: 4111-4118, 1999.

  7. Vlad, L. D., Axiotis, C. A., Merino, M. J., and Green, W. Fatty acid synthase is highly expressed in aggressive thyroid tumors, Modern Pathology. 12: 70A, 1999.

  8. Pizer, E., Lax, S., Kuhajda, F.P., Pasternack, G.R., and Kurman, R. Fatty acid synthase expression in endometrial carcinoma: correlation with cell proliferation and hormone receptors, Cancer. 83: 528-537, 1998.

  9. Friedman, R., Seal, E., Venema, V., Pochet, M., and Hennigar, R. Clinical implications of fatty acid synthase (FAS) in pediatric tumor cell lines, FAESB J. 11: A109, 1997.

  10. Gansler, T. S., Hardman, W., III, Hunt, D. A., Schaffel, S., and Henninger, R. A. Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival, Human Pathology. 28: 686-692, 1997.

  11. Milgraum, L. Z., Witters, L. A., Pasternack, G. R., and Kuhajda, F. P. Enzymes of the fatty acid synthesis pathway are highly expressed in in-situ breast carcinoma, Clinical Cancer Research. 3: 2115-2120, 1997.

  12. Alo, P. L., Visca, P., Marci, A., Mangoni, A., Botti, C., and Di Tondo, U. Expression of fatty acid synthase (FAS) as a predictor of recurrence in stage I breast carcinoma patients, Cancer. 77: 474-482, 1996.

  13. Hahnel, R. Prospective study of fatty acid synthase (FAS) expression in breast cancer and progression of disease, International Journal of Oncology. 9: 253-255, 1996.

  14. Pizer, E. S., Kurman, R. J., Pasternack, G. R., and Kuhajda, F. P. Expression of fatty acid synthase is closely linked to proliferation and stromal decidualization in cycling endometrium, International Journal of Gynecological Pathology. 16: 45-51, 1996.

  15. Shurbaji, M. S., Kalbfleisch, J. H., and Thurmond, T. S. Immunohistochemical detection of a fatty acid synthase (OA-519) as a predictor of progression of prostate cancer, Human Pathology. 27: 917-921, 1996.

  16. Epstein, J. I., CarMichael, M., and Partin, A. W. OA-519 (fatty acid synthase) as in independent predictor of pathologic stage in adenocarcinoma of the prostate, Urology. 45: 81-86, 1995.

  17. Jensen, V., Ladekarl, M., Holm-Nielsen, P., Melsen, F., and Soerensen, F. B. The prognostic value of oncogenic antigen 519 (OA-519) expression and proliferative activity detected by antibody MIB-1 in node-negative breast cancer, Journal of Pathology. 176: 343-352, 1995.

  18. Bobrow, L. G., Happerfield, L. C., Pasternack, G. R., and Smith, P. The expression of fatty acid synthase in primary breast cancer: Is it related to prognosis? In: 168th Meeting of the Pathological Society of Great Britain and Ireland, London, England, 1994, pp. 125a.

  19. CarMichael, M. J., Partin, A. W., and Epstein, J. I. OA519 (fatty acid synthase) a novel prognostic marker for prostate cancer: Correlation with pathological stage. In: 89th Annual Meeting of the American Urological Association, San Francisco, California, 1994, pp. 469s.

  20. Bobrow, L. G., Happerfield, L. C., Pasternack, G. R., Smith, P., and Owens, A. H. The expression of fatty acid synthase in primary breast cancer: Is it an independent prognostic indicator? In: Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, 1993.

  21. Jensen, V., Holm-Nielsen, P., and Melsen, F. OA-519 expression in node negative breast cancer. In: 16th Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, 1993.

  22. Shurbaji, M. S., Kuhajda, F. P., Pasternack, G. R., and Thurmond, T. S. Expression of oncogenic antigen 519 (OA-519) in prostate cancer is a potential prognostic indicator, American Journal of Clinical Pathology. 97: 686-691, 1992.

  23. Shurbaji, M. S., Pasternack, G. R., and Kuhajda, F. P. Expression of haptoglobin-related protein in primary and metastatic breast cancers. A longitudinal study of 48 fatal tumors, American Journal of Clinical Pathology. 96: 238-242, 1991.
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